What Research supports hyperbaric oxygen Therapy?

These videos explore the reasons why some individuals may not experience the expected improvements with hyperbaric oxygen therapy, discussing potential factors and considerations.

Research Around HBOT!

  • This study investigates how exposure to hyperbaric air influences stem cell mobilization in humans, offering insights into the hormetic dose-response relationship.

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  • A new study looked at how mild hyperbaric oxygen therapy (HBOT) helps athletes recover after hard workouts. Twelve male athletes did intense cycling, then either rested or used a mild HBOT chamber (slightly higher air pressure and more oxygen). The HBOT group felt less tired, had better heart rate recovery, and showed lower levels of stress in their blood. One session helped a little, but doing it six times made a big difference. This means mild HBOT could be a safe, effective way to help athletes recover faster after exercise.

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  • A review of 11 clinical studies found that mild hyperbaric oxygen therapy (HBOT), especially at 1.5 ATA with oxygen, helps adults with long-term symptoms from mild traumatic brain injuries feel and think better. After about 40 sessions, patients showed clear improvements in memory, focus, and overall symptoms. Lower or higher pressures had mixed results. Because these studies meet top evidence standards, doctors can strongly recommend using HBOT for lasting concussion symptoms—especially for patients also facing PTSD.


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  • A study of 13 healthy older adults (around 68 years old) found that daily mild hyperbaric oxygen therapy (HBOT) for three months helped the skin look and act younger. After the treatment, their skin showed more collagen (which adds firmness), longer elastic fibers, more blood vessels, and fewer old or damaged cells—all signs of healthier, younger skin. In short, HBOT may help slow down aging in human skin by repairing it from the inside.

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  • A study with 49 women who have fibromyalgia compared three treatments: low‑pressure hyperbaric oxygen therapy (HBOT), exercise, and no treatment. Only the HBOT group felt less tired and had less pain at rest. Both HBOT and exercise improved strength, endurance, and how well they did daily tasks—but exercise didn’t reduce fatigue or pain like HBOT did. This means low‑pressure HBOT may be especially good for helping fibromyalgia patients feel less sore and worn out, while also boosting their fitness and function.

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  • A scientific review found that hyperbaric oxygen therapy (HBOT) can make our cells’ "powerhouses"—the mitochondria—work better. Short treatments might temporarily stress cells, but longer or repeated HBOT increases antioxidant defenses, lowers harmful molecules called reactive oxygen species (ROS), and improves overall cell energy. This suggests HBOT could help treat diseases linked to tired or damaged mitochondria by helping restore balance and cell health.

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